J. Antibiot. 60(2): 162–165, 2007
نویسندگان
چکیده
Two new highly oxidized humulane sesquiterpenes, mitissimols D (1) and E (2) were isolated from the fruiting bodies of Lactarius mitissimus. Their structures were elucidated using extensive spectroscopic techniques including 1D and 2D NMR spectra.
منابع مشابه
J. Antibiot. 60(2): 158–161, 2007
A new nucleosidyl-peptide antibiotic, sansanmycin, was isolated from an unidentified Streptomyces sp SS. The structure of sansanmycin was elucidated by analyses of its alkaline hydrolysate and spectroscopic analyses. Sansanmycin exhibits antibacterial activity against Mycobacterium tuberculosis H37Ra and Pseudomonas aeruginosa with MIC values of 10 and 12.5 mg/ml, respectively.
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We examined the effects of halogens on the production of salinosporamide A (NPI-0052) by the obligate marine actinomycete Salinispora tropica NPS465, specifically the production of analogs containing halogens other than chlorine. Adding NaF, NaBr and NaI directly to the production medium prepared in seawater containing 3% NaCl did not induce the production of the corresponding analogs. Replacin...
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1 Isaacs, A., and J. Lindenmann, Proc. Roy. Soc. (London), B147, 258 (1957). 2 Rotem, Z., R. A. Cox, and A. Isaacs, Nature, 197, 564 (1963). 3Abbreviations: RNA and DNA, ribonucleic acid and deoxyribonucleic acid; RNAase, pancreatic ribonuclease; DNAase, pancreatic deoxyribonuclease; CE cells, chick embryo cells. 4O'Dell, T. B., H. N. Wright, and R. N. Bieter, J. Pharmacol. Exptl. Therap., 107,...
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